brain-derivedneurotrophicfactor相关论文
目的:探讨血清脑源性神经营养因子（brain-derived neurotrophic factor, BDNF）与急性缺血性卒中患者卒中后认知损害（post-stroke cogn......
目的:评价脑源性神经营养因子(BDNF)/酪氨酸激酶受体B(TrkB)信号通路在17β雌二醇减轻多次丙泊酚麻醉致发育期大鼠远期认知功能障......
脑源性神经营养因子（BDNF）是成人脑内含量最丰富的神经营养因子，具有显著的脑损伤修复能力。最近的多项研究表明，BNDF在脑卒中后的多种......
Previous studies on the mechanisms of peripheral nerve injury (PNI) have mainly focused on the pathophysiological change......
Traumatic brain injury (TBI) is a serious condition in which trauma to the head causes damage to the brain, leading to a......
Peripheral nerve fibroblasts play a critical role in nerve development and regeneration. Our previous study found that p......
Glaucoma is one of the world\'s most frequent visual impairment causes and leads to selective damage to retinal gangli......
Cerebral dopamine neurotrophic factor transfection in dopamine neurons using neurotensin-polyplex na
Overexpression of neurotrophic factors in nigral dopamine neurons is a promising approach to reverse neurodegeneration o......
Diffusion tensor imaging of the hippocampus reflects the severity of hippocampal injury induced by g
At present, predicting the severity of brain injury caused by global cerebral ischemia/reperfusion injury (GCI/RI) is a ......
Effects of electroacupuncture on the functionality of NG2-expressing cells in perilesional brain tis
Neural/glial antigen 2 (NG2)-expressing cells has multipotent stem cell activity under cerebral ischemia. Our study exam......
Electroacupuncture treatment improves motor function and neurological outcomes after cerebral ischem
Electroacupuncture (EA) has been widely used for functional restoration after stroke. However, its role in post-stroke r......
Immunopotentiator Thymosin Alpha-1 Promotes Neurogenesis and Cognition in the Developing Mouse via a
In early life,the immune system plays an essential role in brain development.In our study,the immunopotentiator thymosin......
Human Brain Slice Culture: A Useful Tool to Study Brain Disorders and Potential Therapeutic Compound
Investigating the pathophysiological mechanisms underlying brain disorders is a priority if novel therapeutic strategies......
Impact of BDNF/TrkB signaling on functional recovery across motor behaviors after cervical spinal co
A C2 cervical spinal cord hemisection(SH)disrupts descending inspiratory-related drive to phrenic motoneurons,paralyzing......
Effect of controlled release of brain-derived neurotrophic factor and neurotrophin-3 from collagen g
This study aimed to examine the effect of controlled releaseof brain-derived neurotrophic factor (BDNF) and neurotrophin......
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Differential regulation of GSK3β in spinal dorsal horn and in hippocampus contributes to neuropathic
Objective Glycogen synthase kinase 3β(GSK3β)inhibitor is proposed as an attractive candidate for the treatment of cogn......
Objective Geranylgeranyltransferase Ⅰ (GGT Ⅰ) is a prenyltransferase that mediates lipid modification of Rho small GTP......
The role of phosphatidylinositol-linked D1-like receptor agonist SKF83959 in major depressive disord
Aim: Growing evidence indicates a relationship between dopamine system and depression, and some dopamine receptor agonis......
Brain-derived neurotrophic facter prevents against amyloid β protein-induced impairment of hippocamp
Introduction: Brain-derived neurotrophic factor (BDNF) improved the spatial learning and memory impaired by accumulated ......
Sigma-1 receptors are involved in the pathophysiological process of several neuropsychiatric diseases such as epilepsy,d......
The Study of Brain-Derived Neurotrophic Factor Composite Conduits on Sciatic Nerve Regeneration in R
Biodegradable drug delivery carder is valuable in the treatment of peripheral nerve injury.In this study, biodegradable ......
Induction of spinal GluN2B-dependent LTP via BDNF contributes to the development of neuropathic pain
In previous studies,we have found that the GluN2B-containing NMDA(NMDA-GluN2B)receptors-mediated long-term potentiation(......
Neural stem cells overexpressing brain-derived neurotrophic factor improve cell survival through Ras
Our previous studies indicated that the transplantation of rat embryonic-derived neural stem cells (NSCs) overexpressing......
The up-regulation of BDNF mRNA on focal cerebral ischemia-reperfusion injury in rats with polysaccha
AIM To study the effect of polysaccharides from Opuntia Milpa Alta (MAPs) on mRNA expression of brain-derived neurotroph......
Aim We hypothesized that BDNF gene (Val66Met) was associated with MET abuse and impulsivity in MET-abuse patients.Method......
Effect of exogenous thyroxine treatment on the postnatal development of brain-derived neurotrophic f
Maternal alcohol abuse is thought to be the common cause of mental retardation.Especially,continuous alcohol consump-tio......
Effect of early thyroxine treatment on brain-derived neurotrophic factor level during the developmen
This study was designed to investigate the effect of early thyroxine (T4) treatment on brain-derived neurotrophic factor......
Cornel iridoid glycoside protects against white matter lesions induced by cerebral ischemia via acti
Ischemic stroke often elicits profound white matter lesions,which results in poor neurological outcomes and impairing th......
The ability of learning and memory declines in all mammals during depression.This damage is caused by many cellular even......
Demethylation regulation of BDNF gene expression in dorsal root ganglion neurons is implicated in op
Repeated administration of morphine may result in opioid-induced hyperalgesia (OIH), which involves altered expression o......
Toll-Like Receptor-4/p38 Mitogen-Activated Protein Kinase (MAPK) Signaling in the Dorsal Horn Partia
Background: Our previous research suggested that the microglial P2X4 purinoceptor (P2X4R) is involved in the activation ......
Effects of estrogen treatment on behavior and expression of BDNF and p TrkB in prefrontal cortex and
To determine the effect of estrogen(E2) on behavior changes of depression, and expression profiles of brain-derived neur......
EXTINCTION OF AVERSIVE MEMORIES ASSOCIATED WITH MORPHINE WITHDRAWAL REQUIRES ERK-MEDIATED EPIGENETIC
Recent evidence suggests that histone deacetylase (HDAC) inhibitors facilitate extinction of rewarding memory of drug ta......
Brain-derived neurotrophic factor serum levels in heroin-dependent patients after 26 weeks of withdr
Brain-derived neurotrophic factor (BDNF) has been implicated in the pathophysiology of heroin dependence.BDNF expression......
AIM Our previous study has demonstrated the therapeutic potential of bone marrow derived-neural stem cells (BM-NSCs) in ......
It is well known that brain is sensitive to ischemia/reperfusion (I/R) induced injury.α-lipoic acid (LA), a free radica......
Effect of early thyroxine treatment on the development of offspring rat cerebellar cortex during mat
Maternal alcohol abuse is one of the most prominent causes of mental retardation among children in China.Thyroid hormone......
Glehnia littoralis Extract Promotes Neurogenesis in the Hippocampal Dentate Gyrus of the Adult Mouse
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Expression of Brain-derived Neurotrophic Factor and Tyrosine Kinase B in Cerebellum of Poststroke De
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Combined therapy of methylprednisolone and brain-derived neurotrophic factor promotes axonal regener
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Brain-derived neurotrophic factor inducing angiogenesis through modulation of matrix-degrading prote
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围手术期神经认知障碍（perioperative neurocognitive disorder, PND）发生率高，危害大，但机制不清，阐明其病理机制，研发有效的防治措施具......
Early paternal deprivation alters levels of hippocampal brain-derived neurotrophic factor and glucoc
Fathers play an important role in the development of brain and species typical behavior like mother in monogamous m......
OBJECTIVE Sigma-1 receptors are involved in the pathophysiological process of several neuropsychiatric diseases such......
